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Figure 5: Paricalcitol improves the protein expression of fibroblast growth factor-23 (FGF23)-fibroblast growth factor receptor-1 (FGFR1)-Klotho and vitamin D receptor (VDR) suppressed by isoproterenol. Quantitative immunoblotting and densitometric analysis demonstrated the expression levels of (a) transforming growth factor-beta 1, (b) FGF23, (c) Klotho, (d) FGFR1, and (e) VDR in rat heart tissue. Values are presented as mean ± standard error of the mean; n = 3. *P < 0.05 compared to the control group, #P < 0.05 compared to the isoproterenol group. |
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