Figure 6: Repressive effect of miR-187-3p mimic on malignant phenotypes of prostate cancer cells was rescued through upregulating FGFRL1. (a) Quantitative real-time reverse transcription polymerase chain reaction was utilized to examine FGFRL1 level in PC-3 cells of 4 groups (NC-mimic + oe-NC, miR-187-3p-mimic + oe-NC, NC-mimic + oe-FGFRL1, and miR-187-3p-mimic + oe-FGFRL1). (b) Western blot was employed for measuring FGFRL1 protein level in PC-3 cells of 4 groups. (c) MTT was done to test the proliferative ability of PC-3 cells in 4 groups. (d) Colony formation assay was conducted for evaluating the colony formation property of PC-3 cells in 4 groups. (e) A wound healing assay was introduced for examination of the migratory capacity of PC-3 cells in 4 groups (magnification: ×40). (f) Cell invasion assay was launched for testing the invasive capacity of PC-3 cells in 4 groups (magnification: ×100). *P < 0.05 relative to NC-mimic + oe-NC group, #P < 0.05 relative to NC-mimic + oe-FGFRL1 group, n = 3.