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  Indian J Med Microbiol
 

Figure 4: Repressive impact of sh-VPS9D1-AS1 on phenotype progression is rescued by downregulating miR-187-3p. (a) qRT-PCR was done to test miR-187-3p level in PC-3 cells in 3 groups (sh-NC + NC-inhibitor, sh-VPS9D1-AS1 + NC-inhibitor, and sh-VPS9D1-AS1 + miR-187-3p-inhibitor). (b) MTT assay detected the proliferative capacity of PC-3 cells in 3 groups. (c) Colony formation assay was carried out to examine the colony formation ability of PC-3 cells in 3 groups. (d) Wound healing assay was launched to assess the migratory property of PC-3 cells in three groups (magnification: ×40). (e) Cell invasion assay estimated the invasive property of PC-3 cells in 3 groups (magnification: ×100). *P < 0.05 relative to sh-NC + NC-inhibitor group, #P < 0.05 relative to sh-VPS9D1-AS1 + NC-inhibitor group, n = 3. NC: Negative controls.

Figure 4: Repressive impact of sh-VPS9D1-AS1 on phenotype progression is rescued by downregulating miR-187-3p. (a) qRT-PCR was done to test miR-187-3p level in PC-3 cells in 3 groups (sh-NC + NC-inhibitor, sh-VPS9D1-AS1 + NC-inhibitor, and sh-VPS9D1-AS1 + miR-187-3p-inhibitor). (b) MTT assay detected the proliferative capacity of PC-3 cells in 3 groups. (c) Colony formation assay was carried out to examine the colony formation ability of PC-3 cells in 3 groups. (d) Wound healing assay was launched to assess the migratory property of PC-3 cells in three groups (magnification: ×40). (e) Cell invasion assay estimated the invasive property of PC-3 cells in 3 groups (magnification: ×100). *<i>P</i> < 0.05 relative to sh-NC + NC-inhibitor group, <sup>#</sup><i>P</i> < 0.05 relative to sh-VPS9D1-AS1 + NC-inhibitor group, <i>n</i> = 3. NC: Negative controls.