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Figure 6: SLP-2 contributed to the viability and invasion of breast cancer cells via ERK pathway. (a) CCK-8 assays were performed to detect the effects of U0126 on the viability of BT-474 and MX-1 cells upon the transfection of SLP-2 overexpression of SLP-2. (b) Transwell assays were performed to detect the effects of U0126 on the migration of BT-474 and MX-1 cells upon the transfection of SLP-2 overexpression of SLP-2. Data are presented as mean ± SEM. ***P < 0.001. SLP-2: Stomatin-like protein-2, SEM: Standard error of the mean, CCK-8: Cell counting kit-8. |
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