Figure 5: Knockdown of FKBP3 suppressed NPC cell growth, invasion and migration via reducing HDAC2 expression. The HK1 and C666-1 cells were co-transfected with siNC or siFKB3#2 and pcDNA3-HDAC2 (named HDAC2) or pcDNA3 vector (named NC). (a) The cell viability was measured by CCK-8 assay. (b) The cell migration capability was determined by wound healing assay. (c) The cell invasion capability was detected by transwell assay. Each experiment repeated three times. **P < 0.01, ***P < 0.001 versus siNC + NC. ^^P < 0.01, ^^^P < 0.001 versus siFKBP3#2 + NC. NPC: Nasopharyngeal carcinoma.