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  Indian J Med Microbiol
 

Figure 4: FKBP3 activated p65/IL-6 signaling pathway via enhancing HDAC2 expression in NPC cells. (a) The expression p-p65, p65 and HDAC2 were examined by western blot. (b and c) The mRNA level and concentration of FKBP3 were determined by qRT-PCR and commercial ELISA kit. (d) Through overexpressing HDAC2 in knockdown FKBP3 cells, the expression of p-p65, p65, and HDAC2 was detected by western blot. (e and f) The mRNA level and concentration of FKBP3 were determined by qRT-PCR and commercial ELISA kit. Each experiment repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001. ^P < 0.05, ^^P < 0.01, ^^^P < 0.001 versus siFKBP3. NPC: Nasopharyngeal carcinoma, qRT-PCR: Quantitative reverse transcription polymerase chain reaction.

Figure 4: FKBP3 activated p65/IL-6 signaling pathway via enhancing HDAC2 expression in NPC cells. (a) The expression p-p65, p65 and HDAC2 were examined by western blot. (b and c) The mRNA level and concentration of FKBP3 were determined by qRT-PCR and commercial ELISA kit. (d) Through overexpressing HDAC2 in knockdown FKBP3 cells, the expression of p-p65, p65, and HDAC2 was detected by western blot. (e and f) The mRNA level and concentration of FKBP3 were determined by qRT-PCR and commercial ELISA kit. Each experiment repeated three times. *<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001. ^<i>P</i> < 0.05, ^^<i>P</i> < 0.01, ^^^<i>P</i> < 0.001 versus siFKBP3. NPC: Nasopharyngeal carcinoma, qRT-PCR: Quantitative reverse transcription polymerase chain reaction.