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  Indian J Med Microbiol
 

Figure 3: Knockdown of FKBP3 suppressed NPC invasion and migration in vitro. (a and b) The cell migration capability of HK1 and C666-1 cells was determined by wound healing assay. (c and d) The invasion capability of HK1 and C666-1 cells was detected by transwell assay. (e) The related proteins expression were evaluated by western blot, including MMP2, MMP9, E-cadherin and N-cadherin. (f) The concentrations of MMP2 and MMP9 were assessed by ELISA kits, respectively. Each experiment repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001 versus siNC. ^P < 0.05, ^^P < 0.01, ^^^P < 0.001 versus NC. NPC: Nasopharyngeal carcinoma.

Figure 3: Knockdown of FKBP3 suppressed NPC invasion and migration <i>in vitro.</i> (a and b) The cell migration capability of HK1 and C666-1 cells was determined by wound healing assay. (c and d) The invasion capability of HK1 and C666-1 cells was detected by transwell assay. (e) The related proteins expression were evaluated by western blot, including MMP2, MMP9, E-cadherin and N-cadherin. (f) The concentrations of MMP2 and MMP9 were assessed by ELISA kits, respectively. Each experiment repeated three times. *<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001 versus siNC. ^<i>P</i> < 0.05, ^^<i>P</i> < 0.01, ^^^<i>P</i> < 0.001 versus NC. NPC: Nasopharyngeal carcinoma.