Figure 3: Knockdown of FKBP3 suppressed NPC invasion and migration in vitro. (a and b) The cell migration capability of HK1 and C666-1 cells was determined by wound healing assay. (c and d) The invasion capability of HK1 and C666-1 cells was detected by transwell assay. (e) The related proteins expression were evaluated by western blot, including MMP2, MMP9, E-cadherin and N-cadherin. (f) The concentrations of MMP2 and MMP9 were assessed by ELISA kits, respectively. Each experiment repeated three times. *P < 0.05, **P < 0.01, ***P < 0.001 versus siNC. ^P < 0.05, ^^P < 0.01, ^^^P < 0.001 versus NC. NPC: Nasopharyngeal carcinoma.