Figure 1: FKBP3 expression was elevated in NPC patients and cells. (a) Enhanced expression of FKBP3 mRNA level in NPC tissues compared to normal subjects (normal = 44 and primary tumor = 520). The Ualcan database (ualcan.path.uab.edu) analyzed that FKBP3 expression was associated with tumor grade, but was not related to age and tumor stages. (b) PrognoScan database (http://dna00.bio.kyutech.ac.jp/PrognoScan/index.html) predicted that high FKBP3 expression predicted poor prognosis in NPC patients. (c) The FKBP3 mRNA level in nasopharyngeal epithelial cell line (NP-69) and NPC cell lines (HK1 and C666-1) were detected by qRT-PCR. (d) The protein level of FKBP3 in NP-69, HK1, and C666-1 cells. Each experiment repeated three times. **P < 0.01, ***P < 0.001. NPC: Nasopharyngeal carcinoma, qRT-PCR: Quantitative reverse transcription polymerase chain reaction.

http://dna00.bio.kyutech.ac.jp/PrognoScan/index.html) predicted that high FKBP3 expression predicted poor prognosis in NPC patients. (c) The FKBP3 mRNA level in nasopharyngeal epithelial cell line (NP-69) and NPC cell lines (HK1 and C666-1) were detected by qRT-PCR. (d) The protein level of FKBP3 in NP-69, HK1, and C666-1 cells. Each experiment repeated three times. **P < 0.01, ***P < 0.001. NPC: Nasopharyngeal carcinoma, qRT-PCR: Quantitative reverse transcription polymerase chain reaction.">