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  Indian J Med Microbiol
 

Figure 3: PCA inhibits H2O2-induced oxidative stress levels in RA-FLSs. (a and b) The ROS level in H2O2-induced MH7A cells treated by PCA was detected by DCFDA staining. (c and d) The levels of MDA and SOD in H2O2-induced MH7A cells treated by PCA were determined by respective ELISA assay kits. ***P < 0.001 versus control group. #P < 0.05 and ###P < 0.001 versus H2O2 (5 μM) group. PCA: Protocatechuic acid, RA-FLSs: Rheumatoid arthritis fibroblast-like synoviocytes, MDA: Malonaldehyde, SOD: Superoxide dismutase, ELISA: Enzyme-linked immunosorbent assay.

Figure 3: PCA inhibits H<sub>2</sub>O<sub>2</sub>-induced oxidative stress levels in RA-FLSs. (a and b) The ROS level in H<sub>2</sub>O<sub>2</sub>-induced MH7A cells treated by PCA was detected by DCFDA staining. (c and d) The levels of MDA and SOD in H<sub>2</sub>O<sub>2</sub>-induced MH7A cells treated by PCA were determined by respective ELISA assay kits. ***<i>P</i> < 0.001 versus control group. <sup>#</sup><i>P</i> < 0.05 and <sup>###</sup><i>P</i> < 0.001 versus H<sub>2</sub>O<sub>2</sub> (5 μM) group. PCA: Protocatechuic acid, RA-FLSs: Rheumatoid arthritis fibroblast-like synoviocytes, MDA: Malonaldehyde, SOD: Superoxide dismutase, ELISA: Enzyme-linked immunosorbent assay.