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  Indian J Med Microbiol
 

Figure 2: PCA inhibits H2O2-induced migration and invasion of RA-FLSs. (a and b) The migration of H2O2-induced MH7A cells treated by PCA was detected by wound healing assay. (c and d) The invasion of H2O2-induced MH7A cells treated by PCA was detected by transwell assay. (e) The expression of proteins associated with migration in H2O2-induced MH7A cells treated by PCA was detected by western blot. ***P < 0.001 versus control group. ##P < 0.01 and ###P < 0.001 versus H2O2 (5 μM) group. PCA: Protocatechuic acid, RA-FLSs: Rheumatoid arthritis fibroblast-like synoviocytes.

Figure 2: PCA inhibits H<sub>2</sub>O<sub>2</sub>-induced migration and invasion of RA-FLSs. (a and b) The migration of H<sub>2</sub>O<sub>2</sub>-induced MH7A cells treated by PCA was detected by wound healing assay. (c and d) The invasion of H<sub>2</sub>O<sub>2</sub>-induced MH7A cells treated by PCA was detected by transwell assay. (e) The expression of proteins associated with migration in H<sub>2</sub>O<sub>2</sub>-induced MH7A cells treated by PCA was detected by western blot. ***<i>P</i> < 0.001 versus control group. <sup>##</sup><i>P</i> < 0.01 and <sup>###</sup><i>P</i> < 0.001 versus H<sub>2</sub>O<sub>2</sub> (5 μM) group. PCA: Protocatechuic acid, RA-FLSs: Rheumatoid arthritis fibroblast-like synoviocytes.