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  Indian J Med Microbiol
 

Figure 1: PCA reduces H2O2-induced proliferation of RA-FLSs. (a) The chemical structure of PCA. (b and c) The viability of MH7A cells with or without H2O2 induction was detected by CCK-8 assay. (d and e) The apoptosis of H2O2-induced MH7A cells treated by PCA was analyzed by TUNEL assay. **P < 0.01 and ***P < 0.001 versus control group. #P < 0.05, ##P < 0.01 and ###P < 0.001 versus H2O2 (5 μM) group. PCA: Protocatechuic acid, RA-FLSs: Rheumatoid arthritis fibroblast-like synoviocytes, CCK-8: Cell counting kit-8, TUNEL: Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling.

Figure 1: PCA reduces H<sub>2</sub>O<sub>2</sub>-induced proliferation of RA-FLSs. (a) The chemical structure of PCA. (b and c) The viability of MH7A cells with or without H<sub>2</sub>O<sub>2</sub> induction was detected by CCK-8 assay. (d and e) The apoptosis of H<sub>2</sub>O<sub>2</sub>-induced MH7A cells treated by PCA was analyzed by TUNEL assay. **<i>P</i> < 0.01 and ***<i>P</i> < 0.001 versus control group. <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01 and <sup>###</sup><i>P</i> < 0.001 versus H<sub>2</sub>O<sub>2</sub> (5 μM) group. PCA: Protocatechuic acid, RA-FLSs: Rheumatoid arthritis fibroblast-like synoviocytes, CCK-8: Cell counting kit-8, TUNEL: Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling.