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  Indian J Med Microbiol
 

Figure 5: Effect of EECR on glucose tolerance and insulin sensitivity in methylglyoxal-treated rats. Oral glucose tolerance test and insulin tolerance tests were carried out on day 84. Blood sugar levels (a) and area under the curve (b) of oral glucose tolerance test. Blood glucose levels (c) and area under the curve (d) of insulin tolerance tests. Two groups of rats were supplemented with saline solution (control group) or methylglyoxal solution (methylglyoxal group) without administration of test materials. The other methylglyoxal-treated rats were supplemented with metformin (10 mg/kg/d), low-dose of EECR (L-EECR, 10 mg/kg/day), middle-dose of EECR (M-EECR, 50 mg/kg/day), and high-dose of EECR (H-EECR, 100 mg/kg/day). Values (means ± standard deviation, n = 6 for the test groups) not sharing the same superscript letter are significantly different (P < 0.05).

Figure 5: Effect of EECR on glucose tolerance and insulin sensitivity in methylglyoxal-treated rats. Oral glucose tolerance test and insulin tolerance tests were carried out on day 84. Blood sugar levels (a) and area under the curve (b) of oral glucose tolerance test. Blood glucose levels (c) and area under the curve (d) of insulin tolerance tests. Two groups of rats were supplemented with saline solution (control group) or methylglyoxal solution (methylglyoxal group) without administration of test materials. The other methylglyoxal-treated rats were supplemented with metformin (10 mg/kg/d), low-dose of EECR (L-EECR, 10 mg/kg/day), middle-dose of EECR (M-EECR, 50 mg/kg/day), and high-dose of EECR (H-EECR, 100 mg/kg/day). Values (means ± standard deviation, <i>n</i> = 6 for the test groups) not sharing the same superscript letter are significantly different (<i>P</i> < 0.05).