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  Indian J Med Microbiol
 

Figure 1: Exercise training and liraglutide treatment improved glucose homeostasis and lipid metabolism. (a) Blood glucose levels in control and treated db mice subjected to exercise, liraglutide, and a combination of exercise and liraglutide for 8 weeks. (b) IPGTT. The mice fasted for 8 h, and then the blood glucose was tested on 0, 15, 30, 60, 90, and 120 min following intraperitoneal glucose injection. (c) Quantification of the AUC from the IPGTT. (d) Plasma insulin levels were determined using insulin ELISA kits. (e) Plasma cholesterol levels in control and treated db mice. (f) Plasma triglyceride levels in db mice and treated db mice. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 compared to the control group. #P < 0.05, ##P < 0.01, ####P < 0.0001, LE compared with LC or EC. Data were expressed as mean ± SD. CS: Control group, EC: Exercise group, LC: Liraglutide group, LE: Liraglutide and exercise group, IPGTT: Intraperitoneal glucose tolerance test, AUC: Area under the curve, SD: Standard deviation.

Figure 1: Exercise training and liraglutide treatment improved glucose homeostasis and lipid metabolism. (a) Blood glucose levels in control and treated db mice subjected to exercise, liraglutide, and a combination of exercise and liraglutide for 8 weeks. (b) IPGTT. The mice fasted for 8 h, and then the blood glucose was tested on 0, 15, 30, 60, 90, and 120 min following intraperitoneal glucose injection. (c) Quantification of the AUC from the IPGTT. (d) Plasma insulin levels were determined using insulin ELISA kits. (e) Plasma cholesterol levels in control and treated db mice. (f) Plasma triglyceride levels in db mice and treated db mice. *<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001, and ****<i>P</i> < 0.0001 compared to the control group. <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01, <sup>####</sup><i>P</i> < 0.0001, LE compared with LC or EC. Data were expressed as mean ± SD. CS: Control group, EC: Exercise group, LC: Liraglutide group, LE: Liraglutide and exercise group, IPGTT: Intraperitoneal glucose tolerance test, AUC: Area under the curve, SD: Standard deviation.