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  Indian J Med Microbiol
 

Figure 5: Effects of Gap26 on VEGF and Ang-1 after BYHWD treatment at 7 days post MCAO (mean ± SEM, n = 6). (a) Immunofluorescent staining of vascular endothelial growth factor in hippocampal CA1, CA3, and dentate gyrus. Blue was staining of DAPI (cell nuclei), and green was staining of VEGF. (b-d) Quantitative analysis of VEGF in CA1, CA3, and dentate gyrus, respectively. The middle panel indicated the location of staining. (e) Immunofluorescent staining of Ang-1 in hippocampal CA1, CA3, and dentate gyrus. Blue was staining of DAPI (cell nuclei), and green was staining of Ang-1. (f-h) Quantitative analysis of Ang-1 in CA1, CA3, and dentate gyrus, respectively. *P < 0.05 versus Sham, #P < 0.05 versus MCAO, and P < 0.05 versus BYHWD. Scale bar: 20 μm. BYHWD: Buyang Huanwu decoction; MCAO: Middle cerebral artery occlusion; VEGF: Vascular endothelial growth factor; Ang-1: Angiopoietin-1.

Figure 5: Effects of Gap26 on VEGF and Ang-1 after BYHWD treatment at 7 days post MCAO (mean ± SEM, <i>n</i> = 6). (a) Immunofluorescent staining of vascular endothelial growth factor in hippocampal CA1, CA3, and dentate gyrus. Blue was staining of DAPI (cell nuclei), and green was staining of VEGF. (b-d) Quantitative analysis of VEGF in CA1, CA3, and dentate gyrus, respectively. The middle panel indicated the location of staining. (e) Immunofluorescent staining of Ang-1 in hippocampal CA1, CA3, and dentate gyrus. Blue was staining of DAPI (cell nuclei), and green was staining of Ang-1. (f-h) Quantitative analysis of Ang-1 in CA1, CA3, and dentate gyrus, respectively. *<i>P</i> < 0.05 versus Sham, <sup>#</sup><i>P</i> < 0.05 versus MCAO, and <i>P</i> < 0.05 versus BYHWD. Scale bar: 20 μm. BYHWD: Buyang Huanwu decoction; MCAO: Middle cerebral artery occlusion; VEGF: Vascular endothelial growth factor; Ang-1: Angiopoietin-1.