Figure 6: Effect of AMPKα inhibitor and mTOR inhibitor on CIHH-enhanced EDR in rat mesenteric arteries. (a) Original recording. (b) Concentration-response curves of endothelium dependent relaxation. Values were mean ± SEM, n = 5–6 in each group. *P < 0.05, **P < 0.01 versus MS; #P < 0.05, ##P < 0.01 versus MS + CIHH. CIHH: Chronic intermittent hypobaric hypoxia; AMPK: Adenosine mono-phosphate-activated protein kinase; mTOR: Mammalian target of rapamycin; MS: Metabolic syndrome; CON: Control.