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  Indian J Med Microbiol
 

Figure 6: Effect of AMPKα inhibitor and mTOR inhibitor on CIHH-enhanced EDR in rat mesenteric arteries. (a) Original recording. (b) Concentration-response curves of endothelium dependent relaxation. Values were mean ± SEM, n = 5–6 in each group. *P < 0.05, **P < 0.01 versus MS; #P < 0.05, ##P < 0.01 versus MS + CIHH. CIHH: Chronic intermittent hypobaric hypoxia; AMPK: Adenosine mono-phosphate-activated protein kinase; mTOR: Mammalian target of rapamycin; MS: Metabolic syndrome; CON: Control.

Figure 6: Effect of AMPKα inhibitor and mTOR inhibitor on CIHH-enhanced EDR in rat mesenteric arteries. (a) Original recording. (b) Concentration-response curves of endothelium dependent relaxation. Values were mean ± SEM, <i>n</i> = 5–6 in each group. *<i>P</i> < 0.05, **<i>P</i> < 0.01 versus MS; <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01 versus MS <i>+</i> CIHH. CIHH: Chronic intermittent hypobaric hypoxia; AMPK: Adenosine mono-phosphate-activated protein kinase; mTOR: Mammalian target of rapamycin; MS: Metabolic syndrome; CON: Control.