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  Indian J Med Microbiol
 

Figure 2: MK-801 inhibits nicotinamide adenine dinucleotide's effects on the expression of immediate-early response genes. 8 mM nicotinamide adenine dinucleotide and/or 40 μM MK-801 were added into the culture medium in the following groups: control group, nicotinamide adenine dinucleotide group, MK-801 group, nicotinamide adenine dinucleotide and MK-801 co-treatment group. (a and b) The mRNA expression levels of immediate-early response genes under different treatments. (c-e) Representative western blottings and quantitative analysis results of protein levels of immediate-early response genes. The data were obtained by one-way ANOVA combined with Bonferroni post hoc test. **P < 0.01, ***P < 0.001, (n = 3).

Figure 2: MK-801 inhibits nicotinamide adenine dinucleotide's effects on the expression of immediate-early response genes. 8 mM nicotinamide adenine dinucleotide and/or 40 μM MK-801 were added into the culture medium in the following groups: control group, nicotinamide adenine dinucleotide group, MK-801 group, nicotinamide adenine dinucleotide and MK-801 co-treatment group. (a and b) The mRNA expression levels of immediate-early response genes under different treatments. (c-e) Representative western blottings and quantitative analysis results of protein levels of immediate-early response genes. The data were obtained by one-way ANOVA combined with Bonferroni <i>post hoc</i> test. **<i>P</i> < 0.01, ***<i>P</i> < 0.001, (<i>n</i> = 3).