Figure 2: Effects of adropin and spexin hormones on serum cytokine profile levels in CKF. G-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-10, IL-12, IL-13, IL-17A, TNF-α in serum samples were assessed by the MAGPIX Luminex system. Data are expressed as mean ± S. D. One-way ANOVA and Mann-Whitney U test were used to evaluate the differences between the groups. **P < 0.01 and *P < 0.05 versus vehicle group. +++P < 0.001, ++P < 0.01 and +P < 0.05 versus CKF group (n = 5).