Figure 2: Effects of a 4-week treadmill training on adult hippocampal neurogenesis in wild-type and L/L mice. (a) Representative micrographs of the DAPI+, bromodeoxyuridine+, and doublecortin+ signal in the dorsal dentate gyrus of wild-type and L/L mice. Scale bar: 100 μm. (b) Quantitative results of the number of bromodeoxyuridine+/doublecortin+ cells (yellow cells indicated by the arrows in the merged panels). (c) Quantitative results of the number of bromodeoxyuridine+ cells (red cells shown in the bromodeoxyuridine panels). (d) Quantitative results of the number of doublecortin+ cells (green cells shown in the doublecortin panels). *P < 0.05, ***P < 0.001, wild-type treadmill running versus wild-type sedentary. #P < 0.05, ##P < 0.01, L/L treadmill running versus wild-type treadmill running; Tukey's multiple comparisons. Numbers given in the parentheses indicate the sample sizes.