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  Indian J Med Microbiol
 

Figure 5: BBB protective effects of linalyl acetate under OGD/R alone or calcium-related ischemic injury (CRII) conditions, measured as decreases in OGD/R- or CRII-induced increases in the level of matrix metalloproteinase-9 in brain endothelial cells. Data are shown as means ± standard error of the mean ##P < 0.01 and ###P < 0.001 versus the NOGD control group; **P < 0.01 versus the OGD-only group; ++P < 0.01 versus the CRII group. NOGD control group, no OGD/R in 1.5 mM [Ca2+]o; OGD/R-only group, oxygen-glucose deprivation/reoxygenation + dimethyl sulfoxide in 1.5 mM [Ca2+]o; OGD/R-LA500 group, OGD/R +500 μM linalyl acetate in 1.5 mM [Ca2+]o; CRII group, OGD/R + dimethyl sulfoxide in 5 mM [Ca2+]o; CRII-LA500 group, OGD/R +500 μM linalyl acetate in 5 mM [Ca2+]o.

Figure 5: BBB protective effects of linalyl acetate under OGD/R alone or calcium-related ischemic injury (CRII) conditions, measured as decreases in OGD/R- or CRII-induced increases in the level of matrix metalloproteinase-9 in brain endothelial cells. Data are shown as means ± standard error of the mean <sup>##</sup><i>P</i> < 0.01 and <sup>###</sup><i>P</i> < 0.001 versus the NOGD control group; **<i>P</i> < 0.01 versus the OGD-only group; <sup>++</sup><i>P</i> < 0.01 versus the CRII group. NOGD control group, no OGD/R in 1.5 mM [Ca<sup>2+</sup>]<sub>o</sub>; OGD/R-only group, oxygen-glucose deprivation/reoxygenation + dimethyl sulfoxide in 1.5 mM [Ca<sup>2+</sup>]<sub>o</sub>; OGD/R-LA500 group, OGD/R +500 μM linalyl acetate in 1.5 mM [Ca<sup>2+</sup>]<sub>o</sub>; CRII group, OGD/R + dimethyl sulfoxide in 5 mM [Ca<sup>2+</sup>]<sub>o</sub>; CRII-LA500 group, OGD/R +500 μM linalyl acetate in 5 mM [Ca<sup>2+</sup>]<sub>o</sub>.