Figure 3: Antioxidative effects of linalyl acetate. (a) The antioxidative effects on increases in intracellular reactive oxygen species. (b) The antioxidative effects on the changes in [Ca2+]i induced by exposure to OGD/R alone or calcium-related ischemic injury (CRII) conditions. Data are shown as means ± standard error of the mean (n = 3–8 per group). #P < 0.05, ##P < 0.01 and ###P < 0.001 versus the NOGD control group; *P < 0.05, **P < 0.01 and ***P < 0.001 versus the OGD/R-only group; +P < 0.05 and +++P < 0.001 versus the CRII group. NOGD control group, no OGD/R in 1.5 mM [Ca2+]o; OGD/R-only group, oxygen-glucose deprivation/reoxygenation + dimethyl sulfoxide in 1.5 mM [Ca2+]o; OGD/R-LA500 group, OGD/R + 500 μM linalyl acetate in 1.5 mM [Ca2+]o; CRII group, OGD/R + dimethyl sulfoxide in 5 mM [Ca2+]o; CRII-LA500 group, OGD/R +500 μM linalyl acetate in 5 mM [Ca2+]o.