Calycosin inhibits gemcitabine-resistant lung cancer cells proliferation through modulation of the LDOC1/GNL3L/NFκB

Chi-Cheng Li¹, Cheng-You Lu², Chiung-Hung Hsu³, Dennis Jine-Yuan Hsieh⁴, Tso-Fu Wang⁵, Tsung-Jung Ho⁶, Wei-Wen Kuo⁷, Cecilia Hsuan Day⁸, Shih-Chieh Liao⁹, Ming-Cheng Chen¹⁰, Chih-Yang Huang^11
1 Center of Stem Cell and Precision Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation; College of Medicine, Tzu Chi University, Hualien, Taiwan
² Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan
³ GeneReach Biotechnology Corp, Taichung, Taiwan
⁴ Clinical Laboratory, Chung Shan Medical University Hospital; School of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan
⁵ College of Medicine, Tzu Chi University; Department of Hematology and Oncology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan
⁶ Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation; School of Post-Baccalaure Chinese Medicine, College of Medicine, Tzu Chi University, Hualien, Taiwan
⁷ Department of Biological Science and Technology; Ph.D. Program for Biotechnology Industry, China Medical University, Taichung, Taiwan
⁸ Department of Nursing, MeiHo University, Pingtung, Taiwan
⁹ Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan
¹⁰ Division of Colorectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung; Faculty of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
¹¹ Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien; Graduate Institute of Biomedical Sciences, China Medical University, Taichung; Department of Biological Science and Technology, Asia University, Taichung; Center of General Education, Buddhist Tzu Chi Medical Foundation, Tzu Chi University of Science and Technology, Hualien; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan

Correspondence Address:
Prof. Chih-Yang Huang
Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien
Taiwan
Dr. Ming-Cheng Chen
Division of Colorectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung
Taiwan

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/cjop.CJOP-D-23-00009